| Cas No. | 50-10-2 |
| 别名 | 奥芬溴铵 |
| 化学名 | 2-[(2-cyclohexyl-2-hydroxy-2-phenylacetyl)oxy]-N,N-diethyl-N-methyl-ethanaminium, monobromide |
| Canonical SMILES | CC[N+](CCOC(C(C1=CC=CC=C1)(O)C2CCCCC2)=O)(C)CC.[Br-] |
| 分子式 | C21H34NO3.Br |
| 分子量 | 428.4 |
| 溶解度 | DMF: 33 mg/ml,DMSO: 25 mg/ml,Ethanol: 33 mg/ml,PBS (pH 7.2): 10 mg/ml |
| 储存条件 | Store at -20°C |
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
| Shipping Condition | Evaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request |
| 产品描述 | Oxyphenonium is an antagonist of muscarinic acetylcholine receptors that binds to muscarinic receptors on isolated guinea pig atria and ileum (Kds = 0.11 and 0.17 nM, respectively). In vivo, oxyphenonium reverses carbaminocholine- and acetylcholine-induced decreases in blood pressure in anesthetized cats (ED50s = 0.591 and 1 μg/kg, respectively). It decreases rumenal ulcer formation in rats and suppresses insulin-induced gastric secretion in dogs with gastric fistulas. Oxyphenonium also prevents form-deprivation myopia (FDM) in a chick model of experimental myopia. Formulations containing oxyphenonium have been used to treat peptic ulcers. |
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