| Cas No. | 14292-27-4 |
| 别名 | 3-羟基辛酸 |
| 化学名 | 3-hydroxy-octanoic acid |
| Canonical SMILES | OC(CC(O)CCCCC)=O |
| 分子式 | C8H16O3 |
| 分子量 | 160.2 |
| 溶解度 | Chloroform: soluble,Ethanol: soluble,Methanol: soluble |
| 储存条件 | Store at -20°C |
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
| Shipping Condition | Evaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request |
| 产品描述 | 3-hydroxy Octanoic acid is a hydroxylated fatty acid that has been found in LPS from P. aeruginosa and the methyl-branched poly(3-hydroxyalkanoate) (PHA) polymers produced by P. oleovorans. It is an agonist of the orphan receptor GPR109B, increasing intracellular calcium in human neutrophils which endogenously express GPR109B. 3-hydroxy Octanoic acid prevents lipolysis of human adipocytes and is upregulated in human plasma in response to a ketogenic diet. Plasma levels of 3-hydroxy Octanoic acid also increase 3.41-fold in human male runners following a treadmill run to exhaustion as well as in a mouse model of autism spectrum disorder (ASD) fed a high-glycemic diet. |
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