Tofacitinib-13C3 (Tasocitinib-13C3) is the 13C-labeled Tofacitinib. Tofacitinib is an orally availableJAK3/2/1inhibitor withIC₅₀s of 1, 20, and 112 nM, respectively.

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs^[1].

315.35

C₁₃¹³C₃H₂₀N₆O

托法替尼 13C3

Room temperature in continental US; may vary elsewhere.

Please store the product under the recommended conditions in the Certificate of Analysis.