CYP4A11/CYP4F2-IN-1

立即咨询

CYP4A11/CYP4F2-IN-1

本产品不向个人销售，仅用作科学研究，不用于任何人体实验及非科研性质的动物实验。

CAS NO:

502654-40-2

包装与价格：

包装	价格(元)
100mg	电议
250mg	电议
500mg	电议

产品介绍

CYP4A11/CYP4F2-IN-1 是一种有效的细胞色素P450 (CYP) 4A11和CYP4F2的双抑制剂，IC₅₀值分别分别为 19 nM 和 17 nM。CYP4A11/CYP4F2-IN-1 具有研究肾脏疾病的潜力。

生物活性

CYP4A11/CYP4F2-IN-1 is a potent dual inhibitor ofcytochrome P450(CYP) 4A11andCYP4F2, withIC₅₀s of 19 nM and 17 nM, respectively. CYP4A11/CYP4F2-IN-1 has potential for the research of renal diseases^[1].

IC₅₀& Target^[1]

CYP4A11

19 nM (IC₅₀)

CYP4F2

17 nM (IC₅₀)

体外研究
(In Vitro)

CYP4A11/CYP4F2-IN-1 (compound 2) inhibits 20-Hydroxyeicosatetraenoic acid (20-HETE) production from arachidonic acid in human renal microsomes, with an IC₅₀of 4.2 nM^[1].

分子量

285.36

Formula

C₁₅H₁₅N₃OS

CAS 号

502654-40-2

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.