Liothyronine sodium hydrate is an active form of thyroid hormone. Liothyronine sodium hydrate is a potent thyroid hormone receptorsTRαandTRβagonist withK_is of 2.33 nM for hTRα and hTRβ, respectively^[1][2][3].

Liothyronine (T3, 100 nM) sodium hydrate stimulates the proliferation of hepatocarcinema cells in which TRβ1 is overexpressed^[1]. Liothyronine sodium hydrate binds to human β1 thyroid hormone receptor (hTRβ1), and changes its conformation. Liothyronine sodium hydrate promotes growth, induces differentiation and regualtes metabolic effects^[2].

C₁₅H₁₂I₃NO₄.xH₂O.Na

345957-19-9

三碘代甲状腺素钠盐水合物

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