Liothyronine hydrochloride

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本产品不向个人销售，仅用作科学研究，不用于任何人体实验及非科研性质的动物实验。

CAS NO:

6138-47-2

包装与价格：

包装	价格(元)
100mg	电议
250mg	电议
500mg	电议

产品名称

三碘代甲状腺素盐酸盐
Triiodothyronine hydrochloride
3,3',5-Triiodo-L-thyronine hydrochloride
T3 hydrochloride

产品介绍

Liothyronine hydrochloride 是一种有效的甲状腺激素。Liothyronine hydrochloride 是有效的TRα和TRβ激动剂，对 hTRα 和 hTRβ 的K_i值均为 2.33 nM。

生物活性

Liothyronine hydrochloride is an active form of thyroid hormone. Liothyronine hydrochloride is a potent thyroid hormone receptorsTRαandTRβagonist withK_is of 2.33 nM for hTRα and hTRβ, respectively^[1]^[2]^[3].

IC₅₀& Target^[1]

Human Endogenous Metabolite

体外研究
(In Vitro)

Liothyronine (T3, 100 nM) hydrochloride stimulates the proliferation of hepatocarcinema cells in which TRβ1 is overexpressed^[1]. Liothyronine hydrochloride binds to human β1 thyroid hormone receptor (hTRβ1), and changes its conformation. Liothyronine hydrochloride promotes growth, induces differentiation and regualtes metabolic effects^[2].

Clinical Trial

分子量

687.43

Formula

C₁₅H₁₃ClI₃NO₄

CAS 号

6138-47-2

中文名称

三碘代甲状腺素盐酸盐

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.