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Glycolic acid
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Glycolic acid图片
包装与价格:
包装价格(元)
10mM (in 1mL DMSO)电议
1g电议

产品介绍
GlycolicAcid是酪氨酸酶(tyrosinase)的抑制剂,能抑制黑色素的形成,从而减淡皮肤的颜色。

Cell experiment:

HM3KO pigmented human melanoma cells and B16 mouse melanoma cells are cultured in Dulbecco’s modified Eagles medium supplemented with 10%fetal calf serum and appropriate amounts of antibiotics and fungizone were dissolved at a concentration of 100mg/mL in distilled water. These chemicals (e.g., Glycolic Acid ) are added to the cell cultures at final concentrations of 300 or 500 mg/mL every 2 days for 5 days[1].

产品描述

Glycolic Acid is an inhibitor of tyrosinase, suppressing melanin formation and lead to a lightening of skin colour.

Different concentrations of Glycolic Acid (GA) or LA (300 and 500 mg/mL) are tested on the growth of mouse and human melanoma cells. Both types of cells grow well, even in the presence of 300 mg/mL of each chemical for 5 days. However, 500 mg/mL Glycolic Acid inhibits the cell growth of mouse melanoma cells (41%) and humanmelanoma cells (27%), and 500 mg/mL of LA inhibits the growth of mouse melanoma cells (36%)[1].

[1]. Usuki A, et al. The inhibitory effect of glycolic acid and lactic acid on melanin synthesis in melanoma cells. Exp Dermatol. 2003;12 Suppl 2:43-50.