NY-ESO-1(87-111)

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NY-ESO-1(87-111)

本产品不向个人销售，仅用作科学研究，不用于任何人体实验及非科研性质的动物实验。

CAS NO:

508230-31-7

包装与价格：

包装	价格(元)
100mg	电议
250mg	电议
500mg	电议

产品介绍

NY-ESO-1 (87-111) 是一种泛 MHC II 类限制性肽序列。NY-ESO-1 (87-111) 与多个 HLA-DR 和 HLA-DP4 分子结合，并在 HLA-DR 和 HLA-DP4 分子存在的情况下刺激 Th1 型和 Th-2/Th0 型 CD4⁺T 细胞。

生物活性

NY-ESO-1 (87-111) is a pan-MHC class II-restricted peptide sequence. NY-ESO-1 (87-111) binds to multiple HLA-DR and HLA-DP4 molecules, and stimulates Th1-type and Th-2/Th0-typeCD4⁺T cells when presented in the context of HLA-DR and HLA-DP4 molecules^[1].

分子量

2869.40

Formula

C₁₃₁H₂₀₆N₃₂O₃₆S₂

CAS 号

508230-31-7

Sequence

Leu-Leu-Glu-Phe-Tyr-Leu-Ala-Met-Pro-Phe-Ala-Thr-Pro-Met-Glu-Ala-Glu-Leu-Ala-Arg-Arg-Ser-Leu-Ala-Gln

Sequence Shortening

LLEFYLAMPFATPMEAELARRSLAQ

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

Solvent & Solubility

In Vitro:

H₂O

Peptide Solubility and Storage Guidelines:

1. Calculate the length of the peptide.

2. Calculate the overall charge of the entire peptide according to the following table:

	Contents	Assign value
Acidic amino acid	Asp (D), Glu (E), and the C-terminal -COOH.	-1
Basic amino acid	Arg (R), Lys (K), His (H), and the N-terminal -NH₂	+1
Neutral amino acid	Gly (G), Ala (A), Leu (L), Ile (I), Val (V), Cys (C), Met (M), Thr (T), Ser (S), Phe (F), Tyr (Y), Trp (W), Pro (P), Asn (N), Gln (Q)	0

3. Recommended solution:

Overall charge of peptide	Details
Negative (<0)	1. Try to dissolve the peptide in water first. 2. If water fails, add NH₄OH (<50 μL). 3. If the peptide still does not dissolve, add DMSO (50-100 μL) to solubilize the peptide.
Positive (>0)	1. Try to dissolve the peptide in water first. 2. If water fails, try dissolving the peptide in a 10%-30% acetic acid solution. 3. If the peptide still does not dissolve, try dissolving the peptide in a small amount of DMSO.
Zero (=0)	1. Try to dissolve the peptide in organic solvent (acetonitrile, methanol, etc.) first. 2. For very hydrophobic peptides, try dissolving the peptide in a small amount of DMSO, and then dilute the solution with water to the desired concentration.