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Myelin Oligodendrocyte Glycoprotein Peptide(35-55),mouse,rat acetate
本产品不向个人销售，仅用作科学研究，不用于任何人体实验及非科研性质的动物实验。
包装与价格：
包装价格(元)
1mg电议
5mg电议
10mg电议
50mg电议
100mg电议

产品名称
MOG (35-55) (acetate)
产品介绍
Myelin Oligodendrocyte Glycoprotein Peptide (35-55), mouse, rat (MOG (35-55)) acetate 是中枢神经鞘的一个次要成分。Myelin Oligodendrocyte Glycoprotein Peptide (35-55), mouse, rat acetate 有致脑炎活性，诱导 T 细胞增殖。Myelin Oligodendrocyte Glycoprotein Peptide (35-55), mouse, rat acetate 诱导 Th1 细胞因子反应以及相对高水平的 IgG 抗体产生。Myelin Oligodendrocyte Glycoprotein Peptide (35-55), mouse, rat acetate 引发复发缓解性神经系统疾病，伴有广泛的斑块样脱髓鞘。
生物活性

Myelin OligodendrocyteGlycoproteinPeptide (35-55), mouse, rat (MOG (35-55)) acetate is a minor component of CNS myelin. Myelin OligodendrocyteGlycoproteinPeptide (35-55), mouse, rat acetate has encephalitogenic activity and induces T cell proliferative. Myelin OligodendrocyteGlycoproteinPeptide (35-55), mouse, rat acetate induces Th1 cytokine response as well as relatively high levels ofIgGantibodies. Myelin OligodendrocyteGlycoproteinPeptide (35-55), mouse, rat acetate produces a relapsing-remittingneurological diseasewith extensive plaque-like demyelination[1][2][3].

体外研究
(In Vitro)

Myelin Oligodendrocyte Glycoprotein Peptide (35-55), mouse, rat (MOG (35-55); 0-50 μg/mL; 72 h; lymph nodes cells) acetate induces T cell proliferative and secretes Th1 cytokines including IFN-γ, TNF-α, IL-10, IL-4 and IL-5. Myelin Oligodendrocyte Glycoprotein Peptide (35-55), mouse, rat acetate increases the level of IgG[1].

体内研究
(In Vivo)

Myelin Oligodendrocyte Glycoprotein Peptide (35-55), mouse, rat (MOG (35-55); 200 μg (0.2 mL); i.p.; once, for 38 d) acetate has encephalitogenic activity in HLA-DR2 (DRB1*1501) mice[1].

Animal Model:HLA-DR2 (DRB1*1501) mice[1]
Dosage:200 μg (0.2 mL)
Administration:Intraperitoneal injection; once, for 38 days
Result:Resulted in paralysis of both hind and forelimbs.
分子量

2642.00

性状

Solid

Formula

C120H181N35O31S

Sequence Shortening

MEVGWYRSPFSRVVHLYRNGK

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Sealed storage, away from moisture

Powder-80°C2 years
-20°C1 year

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

溶解性数据
In Vitro: 

H2O : 100 mg/mL(37.85 mM;Need ultrasonic)

配制储备液
浓度溶剂体积质量1 mg5 mg10 mg
1 mM0.3785 mL1.8925 mL3.7850 mL
5 mM0.0757 mL0.3785 mL0.7570 mL
10 mM0.0379 mL0.1893 mL0.3785 mL
*

请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液；一旦配成溶液，请分装保存，避免反复冻融造成的产品失效。
储备液的保存方式和期限：-80℃, 6 months; -20℃, 1 month (sealed storage, away from moisture)。-80℃ 储存时，请在 6 个月内使用，-20℃ 储存时，请在 1 个月内使用。