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GnRH Associated Peptide(1-24),human
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
CAS NO:148943-65-1
包装与价格:
包装价格(元)
100mg电议
250mg电议
500mg电议

产品名称
GAP (1-24), human
产品介绍
GnRH Associated Peptide (GAP) (1-24), human 是人类促性腺激素释放激素相关肽 (GAP) 的 1-24 片段 (hGAP-1-24)。GAP 能够通过 3 个氨基酸加工位点与黄体生成素释放激素 (LH-RH) 序列相连。
生物活性

GnRH Associated Peptide (GAP) (1-24), human is the human gonadotropin-releasing hormone-associated peptide (GAP) 1-24 fragment (hGAP-1-24). GAP is joined to the luteinizing hormone-releasing hormone (LH-RH) sequence by a 3 amino acid processing site[1].

体外研究
(In Vitro)

GAP (10 nM; 4 h) stimulates the release of both gonadotropins in anterior pituitaries from female Sprague-Dawley rats, but inhibits the basal secretion of prolactin by ~50%, compared with inhibition levels reported for dopamin, a known prolactin-inhibiting factor[2].
GAP (0.1-10 nM; 3-4 h) inhibits prolactin secretion by 40-45%, with an IC50value of 0.25 nM[2].

分子量

2732.95

Formula

C117H190N32O43

CAS 号

148943-65-1

Sequence Shortening

DAENLIDSFQEIVKEVGQLAETQR

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.