Imipramine-d3 (hydrochloride) is deuterium labeled Imipramine (hydrochloride). Imipramine is an orally active tertiary amine tricyclic antidepressant. Imipramine is aFascin1inhibitor with antitumor activities. Imipramine also inhibitsserotonin transporterwith anIC₅₀value of 32 nM. Imipramine stimulates U-87MG glioma cellsautophagyand induces HL-60 cellapoptosis. Imipramine shows neuroprotective and immunomodulatory effects^{[1][2][3][4][5][6]}.

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs^[1].

319.89

C₁₉H₂₂D₃ClN₂

112898-42-7

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