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Cinchonidine
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Cinchonidine图片
CAS NO:485-71-2
包装:500mg
市场价:294元

产品介绍
Cinchonidine (α-Quinidine) 是一种金鸡纳生物碱,存在于金鸡纳 (Cinchona officinalis) 和 Gongronema latifolium 中。
Cas No.485-71-2
别名辛可尼定; α-Quinidine
Canonical SMILESO[C@H](C1=CC=NC2=CC=CC=C12)[C@H]3[N@@]4C[C@@H](C=C)[C@@H](CC4)C3
分子式C19H22N2O
分子量294.39
溶解度Soluble in DMSO
储存条件4°C, protect from light, stored under nitrogen
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

Cinchonidine (α-Quinidine) is a cinchona alkaloid found in Cinchona officinalis and Gongronema latifolium. A building block used in asymmetric synthesis in organic chemistry. Weak inhibitor of serotonin transporter (SERT) with Kis of 330, 4.2, 36, 196, 15 μM for dSERT, hSERT, hSERT I172M, hSERT S438T, hSERT Y95F, respectively. Antimalarial activities[1].

Cinchonidine (α-Quinidine) is a cinchona alkaloid found in Cinchona officinalis and Gongronema latifolium. A building block used in asymmetric synthesis in organic chemistry. Weak inhibitor of serotonin transporter (SERT) with Kis of 330, 4.2, 36, 196, 15 μM for dSERT, hSERT, hSERT I172M, hSERT S438T, hSERT Y95F, respectively[1].

References:
[1]. Beckman ML, et al. Stereoselective inhibition of serotonin transporters by antimalarial compounds. Neurochem Int. 2014 Jul;73:98-106.