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Dyclonine HCl
本产品不向个人销售，仅用作科学研究，不用于任何人体实验及非科研性质的动物实验。
Dyclonine HCl图片
CAS NO:536-43-6
包装与价格：
包装价格(元)
10mM (in 1mL DMSO)电议
50mg电议

产品介绍
Dyclocaine (Dyclocaine) hydrochloride 是一种口服有效的 ALDH 共价抑制剂（穿过血脑屏障），IC50 为 35 μ；M 为 ALDH2 和 76 ⋼；M 为 ALDH3A1。
Cas No.536-43-6
别名盐酸达克罗宁; Dyclocaine hydrochloride
化学名1-(4-butoxyphenyl)-3-piperidin-1-ylpropan-1-one;hydrochloride
Canonical SMILESCCCCOC1=CC=C(C=C1)C(=O)CCN2CCCCC2.Cl
分子式C18H27NO2.HCl
分子量325.87
溶解度≥ 14.6mg/mL in Ethanol
储存条件Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

Dyclonine hydrochloride is an oral anaesthetic found in Sucrets, an over the counter throat lozenge.Target: Sodium ChannelDyclonine hydrochloride is an oral anaesthetic that is the active ingredient of Sucrets, an over the counter throat lozenge. It is also found in some varieties of the Cepacol sore throat spray. It is a local anesthetic, used topically as the hydrochloride salt. Dyclonine hydrochloride has been found to possess, in addition to its topical anesthetic properties, significant bactericidal and fungicidal activity. Self-sterilizing action manifested by preparations containing the drug was considerably enhanced upon the addition of chlorobutanol. Results of in vitro tests employing microorganisms commonly involved in local infections indicated that the two agents in combination act synergistically [1, 2].

References:
[1]. Florestano, H.J. and M.E. Bahler, Antimicrobial properties of dyclonine hydrochloride, a new topical anesthetic. J Am Pharm Assoc Am Pharm Assoc (Baltim), 1956. 45(5): p. 320-5.
[2]. Gargiulo, A.V., G.M. Burns, and C.P. Huck, Dyclonine hydrochloride--a topical agent for managing pain. Ill Dent J, 1992. 61(4): p. 303-4.