| CAS NO: | 251293-28-4 |
| 包装: | 1mg |
| 市场价: | 2716元 |
| Cas No. | 251293-28-4 |
| 化学名 | (S,Z)-5-(((2S,3R)-1-((S)-2-((Z)-(((S,Z)-1-(((4R,5Z,7S,8Z,10S,11Z,13S,14Z,16S,17Z,19R)-13-((1H-indol-3-yl)methyl)-10-(4-aminobutyl)-16-benzyl-4-((Z)-(((S)-1-carboxy-2-methylpropyl)imino)(hydroxy)methyl)-6,9,12,15,18-pentahydroxy-7-(4-hydroxybenzyl)-1,2-dit |
| Canonical SMILES | CC([C@@](/N=C(O)/[C@]1([H])CSSC[C@@](/N=C(O)/[C@](/N=C(O)/[C@]2([H])CCCN2C([C@](/N=C(O)/[C@](N)([H])CCC(O)=O)([H])[C@@](O)([H])C)=O)([H])CC(O)=O)([H])/C(O)=N/[C@@](/C(O)=N/[C@@](/C(O)=N/[C@@](/C(O)=N/[C@@](/C(O)=N/1)([H])CC3=CC=C(O)C=C3)([H])CCCCN)([H])CC |
| 分子式 | C64H85N13O18S2 |
| 分子量 | 1388.57 |
| 溶解度 | Soluble in 20% acetonitrile / sterile Water |
| 储存条件 | Desiccate at -20°C |
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
| Shipping Condition | Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request |
| 产品描述 | Urotensin II (114-124), human, an 11-amino acid residue peptide, is a potent vasoconstrictor and agonist for the orphan receptor GPR14. Human Urotensin II (U-II) binds to recombinant human GPR14 with high affinity, and the binding is functionally coupled to calcium mobilization. Human Urotensin II induces concentration-dependent increases in intracellular calcium in a HEK-293 cell line expressing human GPR14 (EC50=0:62±0.17 nM, n=6)[1]. Human Urotensin II (U-II) markedly increases total peripheral resistance in anaesthetized non-human primates, a response associated with profound cardiac contractile dysfunction[1]. References: |
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