ML-148 是一种有效的选择性 15-PGDH 抑制剂，IC50 为 56 nM。
| Cas No. | 451496-96-1 |
| Canonical SMILES | O=C(C1=CC=C(N(C2=CC=CC(C)=C2)C=N3)C3=C1)N4CCCCC4 |
| 分子式 | C20H21N3O |
| 分子量 | 319.4 |
| 溶解度 | DMF: 25 mg/ml,DMF:PBS(pH 7.2)(1:1): 0.5 mg/ml,DMSO: 5 mg/ml,Ethanol: 10 mg/ml |
| 储存条件 | Store at -20°C |
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
| Shipping Condition | Evaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request |
| 产品描述 | ML-148 is an inhibitor of 15-hydroxy prostaglandin dehydrogenase (15-PGDH) with an IC50 value of 56 nM. It demonstrates selectivity for 15-PGDH when profiled across a panel of related dehydrogenase or reductase enzymes. |
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