| Cas No. | 23918-98-1 |
| 别名 | 4-(6-氨基-9H-嘌呤-9-基)-4-脱氧-D-赤酮酸 |
| Canonical SMILES | NC1=NC=NC2=C1N=CN2C[C@@H](O)[C@@H](O)C(O)=O |
| 分子式 | C9H11N5O4 |
| 分子量 | 253.2 |
| 溶解度 | 1N HCl: slightly soluble |
| 储存条件 | Store at -20°C |
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
| Shipping Condition | Evaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request |
| 产品描述 | D-Eritadenine is an adenosine analog and a potent, reversible inhibitor of S-adenosylhomocysteine hydrolase (SAAH; IC50 = 7 nM). It inhibits growth of C. parvum parasites (MIC50 = 3 μM) without exhibiting cytotoxicity in HCT-8 cells (CC50 = >1 mM). Dietary administration of D-eritadenine (50 mg/kg) increases liver microsomal phosphatidylethanolamine concentration and decreases liver microsomal δ6 desaturase activity and plasma cholesterol levels in rats. |
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