您好,欢迎来到试剂信息网! [登录] [免费注册]
试剂信息网
位置:首页 > 产品库 > CP-96021 hydrochloride
立即咨询
咨询类型:
     
*姓名:
*电话:
*单位:
Email:
*留言内容:
请详细说明您的需求。
*验证码:
 
CP-96021 hydrochloride
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
CP-96021 hydrochloride图片
CAS NO:167011-22-5
包装与价格:
包装价格(元)
100mg电议
250mg电议
500mg电议

产品介绍
CP-96021 hydrochloride 是一种平衡,有效的口服活性白三烯 D4 (LTD4)/血小板活化因子 (PAF) 受体拮抗剂,Ki值分别为 34 nM 和 37 nM。
生物活性

CP-96021 hydrochloride is a balanced, combined, potent and orally activeleukotriene D4 (LTD4)/platelet activating factor (PAF)receptor antagonist withKivalues of 34 nM and 37 nM, respectively[1].

IC50& Target[1]

LTC4

34 nM (Ki)

Platelet activating factor (PAF) receptor

37 nM (Ki)

体内研究
(In Vivo)

In vivo, CP-96021 inhibits iv LTD4- and iv PAF-induced bronchoconstriction in guinea pigs withED50s of 0.46 and 0.16 mg/kg p.o. respectively. CP-96021 effectively blocks the combined airway obstructive effects of endogenously released PAF and LTD4 stimulated by aerosolized antigen challenge in guinea pigs with anED50s of 1.8 mg/kg p.o[1].

分子量

529.03

Formula

C29H22ClFN4OS

CAS 号

167011-22-5

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.