CAS NO: | 2101737-32-8 |
包装 | 价格(元) |
10 mM * 1 mL in DMSO | 电议 |
5mg | 电议 |
10mg | 电议 |
25mg | 电议 |
50mg | 电议 |
100mg | 电议 |
200mg | 电议 |
生物活性 | VU6000918 is amuscarinic acetylcholine (M4)positive allosteric modulator, with anEC50of 19 nM for hM4[1]. | ||||||||||||||||
IC50& Target | EC50: 19 nM (hM4)[1]. | ||||||||||||||||
体外研究 (In Vitro) | VU6000918 demonstrates statistically significant AHL reversal (18%) from a low oral dose of 0.03 mg/kg and reaches maximal reversal (74%) from a 3 mg/kg dose, with a resultingin vivoplasma EC50of 74 nM (0.66 nM unbound) based on terminal concentrations measured in the study animals (1.5 hr post-administration of 17j)[1]. | ||||||||||||||||
分子量 | 389.42 | ||||||||||||||||
性状 | Solid | ||||||||||||||||
Formula | C18H17F2N5OS | ||||||||||||||||
CAS 号 | 2101737-32-8 | ||||||||||||||||
运输条件 | Room temperature in continental US; may vary elsewhere. | ||||||||||||||||
储存方式 |
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溶解性数据 | In Vitro: DMSO : 125 mg/mL(320.99 mM;Need ultrasonic) 配制储备液
* 请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液;一旦配成溶液,请分装保存,避免反复冻融造成的产品失效。 |