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Zagociguat
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Zagociguat图片
CAS NO:2201048-82-8
包装与价格:
包装价格(元)
5mg电议
10mg电议
25mg电议
50mg电议

产品介绍
Zagociguat 是可溶性鸟苷酸环化酶的刺激剂。Zagociguat 增加一氧化氮 (NO) 信号传导,导致环磷酸鸟苷产量增加。Zagociguat 具有研究非中枢神经系统 (CNS) 疾病的潜力。
Cas No.2201048-82-8
分子式C16H10F4N6
分子量362.28
溶解度DMSO : 250 mg/mL (690.07 mM; Need ultrasonic)
储存条件Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

Zagociguat is the stimulator of soluble guanylate cyclase. Zagociguat increases nitric oxide (NO) signaling leading to an increase in cyclic guanosine monophosphate production. Zagociguat has the potential for the research of noncentral nervous system (CNS) disorders[1].

[1]. Debra J. Wallace, et al. Accelerated Development of a Scalable Synthesis of CY6463, a CNS-Penetrant sGC Stimulator for the Treatment of Neurodegenerative Diseases. Org Process Res Dev. 2021;25(10):2288-2299.