CAS NO: | 162870-29-3 |
包装 | 价格(元) |
10 mM * 1 mL in DMSO | 电议 |
5mg | 电议 |
10mg | 电议 |
50mg | 电议 |
生物活性 | (S)-3,5-DHPG is a weak, but selectivegroup Imetabotropic glutamate receptors(mGluRs)agonist withKivalues of 0.9 μM and 3.9 μM for mGluR1a and mGluR5a, respectively[1]. (S)-3,5-DHPG exhibits anxiolytic activity in rats subjected to hypoxia[2]. | ||||||||||||||||
IC50& Target[1] |
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体外研究 (In Vitro) | (S)-3,5-DHPG specifically displaces high-affinity quisqualate sites, the putative group I mGlu binding sites[1]. | ||||||||||||||||
体内研究 (In Vivo) | (S)-3,5-DHPG (icv; 0.01, 0.1 and 1.0 nmol/5 μL) improves consolidation and retrieval and exhibits anxiolytic activity in dose-dependent manner in male Wistar rats weighing 160-180 g subjected to hypoxia[2]. | ||||||||||||||||
分子量 | 183.16 | ||||||||||||||||
性状 | Solid | ||||||||||||||||
Formula | C8H9NO4 | ||||||||||||||||
CAS 号 | 162870-29-3 | ||||||||||||||||
中文名称 | (S)-3,5-二羟基苯基甘氨酸 | ||||||||||||||||
运输条件 | Room temperature in continental US; may vary elsewhere. | ||||||||||||||||
储存方式 |
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溶解性数据 | In Vitro: DMSO : 100 mg/mL(545.97 mM;Need ultrasonic) H2O : 25 mg/mL(136.49 mM;Need ultrasonic) 配制储备液
* 请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液;一旦配成溶液,请分装保存,避免反复冻融造成的产品失效。 In Vivo: 请根据您的实验动物和给药方式选择适当的溶解方案。以下溶解方案都请先按照In Vitro方式配制澄清的储备液,再依次添加助溶剂: ——为保证实验结果的可靠性,澄清的储备液可以根据储存条件,适当保存;体内实验的工作液,建议您现用现配,当天使用;
以下溶剂前显示的百
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