VU0422288 是 group IIImGluRs的一种正变构调节剂，在钙动员试验中，VU0422288 对 mGluR4、mGluR7和 mGluR8 的EC50值分别为108、146和128 nM。
| 生物活性 | VU0422288 is a positive allosteric modulator of group IIImGluRswithEC50values of 108, 146, and 128 nM formGluR4,mGluR7, andmGluR8, respectively in calcium mobilization assays[1]. |
| IC50& Target | mGluR4 108 nM (EC50) | mGluR7 146 nM (EC50) | mGluR8 128 nM (EC50) |
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| 运输条件 | Room temperature in continental US; may vary elsewhere. |
| 储存方式 | | Powder | -20°C | 3 years | | 4°C | 2 years | | In solvent | -80°C | 6 months | | -20°C | 1 month |
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