CAS NO: | 1703748-89-3 |
包装: | 5mg |
市场价: | 4600元 |
生物活性 | Fosnetupitant (Pronetupitant) a methylene phosphate prodrug of Netupitant. Fosnetupitant (Pronetupitant) exhibits a pKiof 9.5 forhuman NK1receptor[1]. | ||||||||||||||||
体外研究 (In Vitro) | Fosnetupitant (Pronetupitant) displays micromolar affinity for the 5-HT6 (pKi~ 5.2) receptor and type L Ca2+channels (pKi~ 5.7) and does not bind all the other proteins investigated[1]. | ||||||||||||||||
体内研究 (In Vivo) | Pronetupitant is rapidly and extensively converted to Netupitant after i.v. injection in rats[1]. | ||||||||||||||||
分子量 | 688.60 | ||||||||||||||||
性状 | Solid | ||||||||||||||||
Formula | C31H35F6N4O5P | ||||||||||||||||
CAS 号 | 1703748-89-3 | ||||||||||||||||
运输条件 | Room temperature in continental US; may vary elsewhere. | ||||||||||||||||
储存方式 | -20°C, protect from light, stored under nitrogen *In solvent : -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen) | ||||||||||||||||
溶解性数据 | In Vitro: DMSO : 100 mg/mL(145.22 mM;Need ultrasonic) 配制储备液
* 请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液;一旦配成溶液,请分装保存,避免反复冻融造成的产品失效。 |