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Phyllomedusin
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Phyllomedusin图片
CAS NO:26145-48-2
包装与价格:
包装价格(元)
100mg电议
250mg电议
500mg电议

产品介绍
Phyllomedusin,一种速激肽十肽,是一种NK1 受体激动剂。Phyllomedusin 具有血管舒张活性并引起幽门收缩。
生物活性

Phyllomedusin, an tachykinin decapeptide, is aNK1receptoragonist. Phyllomedusin has vasodilating activity and provokes the contraction of the pylorus[1][2][3].

IC50& Target[1]

NK1

 

体外研究
(In Vitro)

Phyllomedusin increases neuronal excitation with psychoactive and behavioral responses[4].
Phyllomedusin can cause smooth muscle contraction and vasodilatation[4].

体内研究
(In Vivo)

Phyllomedusin (30-300 μg/kg, i.p.) delays gastric emptying in conscious rats[2].
Phyllomedusin (0.1 and 5 μg/kg, i.v.) has stimulant activity on the stomach of the anaesthetized rat[3].

Animal Model:Conscious rats[2].
Dosage:30, 100, 300 μg/kg
Administration:Intraperitoneal injection (i.p.)
Result:Caused 75% delay in gastric emptying in conscious rats.
分子量

1171.37

Formula

C52H82N16O13S

CAS 号

26145-48-2

Sequence Shortening

{Pyr}-NPNRFIGLM-NH2

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.