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Gluten Exorphin C
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Gluten Exorphin C图片
CAS NO:142479-62-7
包装与价格:
包装价格(元)
1mg电议
5mg电议
10mg电议
25mg电议
50mg电议
100mg电议

产品介绍
Gluten exorphin C 是一种源自谷朊粉的阿片肽。在 GPI 和 MVD 检测中,抑制μ opioidδ opioid活性,IC50值分别为 40 μM 和13.5 μM。
生物活性

Gluten exorphin C is an opioid peptide derived from wheat gluten. ItsIC50values are 40 μM and 13.5 μM forμ opioidandδ opioidactivities in the GPI and MVD assays, respectively.

IC50& Target

IC50: 40 μM (μ opioid), 13.5 μM (δ opioid)[1]

体外研究
(In Vitro)

Gluten exorphin C, a novel opioid peptide, is isolated from the pepsin-trypsin-chymotrypsin digest of wheat gluten. Gluten exorphin C is evaluated its opioid activities by the GPI and MVD assays and its receptor affinities by radioreceptor assays. Its IC50s are 40 μM and 13.5 μM in the GPI and the MVD assays, respectively. Gluten exorphin C has a structure quite different from any of the endogenous and exogenous opioid peptides ever reported in that the N terminal Tyr is the only aromatic amino acid. The analogs containing Tyr-Pro-X-Ser-Leu are synthesized to study its structure-activity relationship. Peptides in which X is an aromatic amino acid or an aliphatic hydrophobic amino acid has opioid activity[1].

分子量

591.70

性状

Solid

Formula

C29H45N5O8

CAS 号

142479-62-7

Sequence

Tyr-Pro-Ile-Ser-Leu

Sequence Shortening

YPISL

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Sealed storage, away from moisture

Powder-80°C2 years
-20°C1 year

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

溶解性数据
In Vitro: 

H2O : 100 mg/mL(169.00 mM;Need ultrasonic)

配制储备液
浓度溶剂体积质量1 mg5 mg10 mg
1 mM1.6900 mL8.4502 mL16.9005 mL
5 mM0.3380 mL1.6900 mL3.3801 mL
10 mM0.1690 mL0.8450 mL1.6900 mL
*

请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液;一旦配成溶液,请分装保存,避免反复冻融造成的产品失效
储备液的保存方式和期限:-80℃, 6 months; -20℃, 1 month (sealed storage, away from moisture)。-80℃ 储存时,请在 6 个月内使用,-20℃ 储存时,请在 1 个月内使用。

In Vivo:

请根据您的实验动物和给药方式选择适当的溶解方案。以下溶解方案都请先按照In Vitro方式配制澄清的储备液,再依次添加助溶剂:

——为保证实验结果的可靠性,澄清的储备液可以根据储存条件,适当保存;体内实验的工作液,建议您现用现配,当天使用; 以下溶剂前显示的百
分比是指该溶剂在您配制终溶液中的体积占比;如在配制过程中出现沉淀、析出现象,可以通过加热和/或超声的方式助溶

  • 1.

    请依序添加每种溶剂: PBS

    Solubility: 50 mg/mL (84.50 mM); Clear solution; Need ultrasonic

*以上所有助溶剂都可在本网站选购。