CAS NO: | 61214-51-5 |
包装 | 价格(元) |
1mg | 电议 |
5mg | 电议 |
10mg | 电议 |
50mg | 电议 |
100mg | 电议 |
生物活性 | β-Endorphin, human, a prominent endogenous peptide, existing in the hypophysis cerebri and hypothalamus, is an agonist ofopioid receptor, with preferred affinity forμ-opioid receptorandδ-opioid receptor; β-Endorphin, human exhibits antinociception activity. | ||||||
IC50& Target | Opioid receptor[1] | ||||||
体外研究 (In Vitro) | β-Endorphin, human is an agonist of opioid receptor, with preferred affinity for μ-opioid receptor and δ-opioid receptor. β-Endorphin exhibits anti-nociception activity by stimulating ε-opioid receptor, rather than μ-, δ-, and κ-opioid receptor[1]. β-Endorphin has anti-nociception activity. Firstly, β-Endorphin combines together with the opioid receptors in hyperalgesia. Further, β-Endorphin suppresses the release of substance P at the level of spinal cord and blocks the conduction of pain on the primary sensory neurons. Moreover, β-Endorphin activates the endogenous analgesia system located in the CNS. In addition, β-Endorphin inhibits the conduction of pain and agitation of nociceptors to exert an analgesic effect[2]. | ||||||
分子量 | 3464.98 | ||||||
性状 | Solid | ||||||
Formula | C158H251N39O46S | ||||||
CAS 号 | 61214-51-5 | ||||||
Sequence | Tyr-Gly-Gly-Phe-Met-Thr-Ser-Glu-Lys-Ser-Gln-Thr-Pro-Leu-Val-Thr-Leu-Phe-Lys-Asn-Ala-Ile-Ile-Lys-Asn-Ala-Tyr-Lys-Lys-Gly-Glu | ||||||
Sequence Shortening | YGGFMTSEKSQTPLVTLFKNAIIKNAYKKGE | ||||||
中文名称 | β-内啡肽,人 | ||||||
运输条件 | Room temperature in continental US; may vary elsewhere. | ||||||
储存方式 | Sealed storage, away from moisture
*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture) |