CAS NO: | 475193-31-8 |
包装: | 5mg (10 mM * 927 μL in Water) |
市场价: | 5200元 |
生物活性 | 2-Methylthioadenosine diphosphate trisodium is a potentpurinergic P2Yreceptors agonist, withEC50s of 19, 6.2, and 5 nM for human P2Y13, mouse P2Y13 and human P2Y12, respectively. 2-Methylthioadenosine diphosphate trisodium has pEC50s of 8.29 and 5.75 for human P2Y1 and rat P2Y6, respectively. 2-Methylthioadenosine diphosphate trisodium induces platelet aggregation and shape change, and inhibits cyclic AMP accumulation in platelets exposed to prostaglandin E1[1][2][3]. |
体外研究 (In Vitro) | 2-Methylthioadenosine diphosphate trisodium (2-Methylthio-ADP trisodium) is a powerful aggregating agent for human platelets. 2-Methylthioadenosine diphosphate trisodium is also a powerful inhibitor of the accumulation of cyclic AMP in intact platelets exposed to PGE1 and a phosphodiesterase inhibitor[1]. |
分子量 | 539.24 |
性状 | Liquid |
Formula | C11H14N5Na3O10P2S |
CAS 号 | 475193-31-8 |
运输条件 | Room temperature in continental US; may vary elsewhere. |
储存方式 | Solution, -20°C, 2 years |