CAS NO: | 1006028-37-0 |
包装 | 价格(元) |
100mg | 电议 |
250mg | 电议 |
500mg | 电议 |
生物活性 | NF546 is a selective non-nucleotideP2Y11agonist with apEC50of 6.27. NF546 stimulates release of interleukin-8 from human monocyte-derived dendritic cells[1]. |
IC50& Target | pEC50: 6.27 (P2Y11)[1] |
体外研究 (In Vitro) | NF546 is relatively selective for P2Y11 over P2Y1, P2Y2, P2Y4, P2Y6, P2Y12, P2X1, P2X2, and P2X2-X3. NF546 (100 μM; 24 hours) is equi-efficacious in stimulating TSP-1 release and inhibiting the LPS-induced release of IL-12p70 in human monocyte-derived dendritic cells[1]. |
分子量 | 1180.74 |
Formula | C47H44N6Na4O17P4 |
CAS 号 | 1006028-37-0 |
运输条件 | Room temperature in continental US; may vary elsewhere. |
储存方式 | Please store the product under the recommended conditions in the Certificate of Analysis. |