CAS NO: | 1657025-60-9 |
包装 | 价格(元) |
100mg | 电议 |
250mg | 电议 |
500mg | 电议 |
生物活性 | PSB-1114 tetrasodium is a potent, enzymatically stable, and subtype-selectiveP2Y2receptoragonist with anEC50of 134 nM. PSB-1114 tetrasodium displays >50-fold selectivity versus the P2Y4(EC50of 9.3 μM) and P2Y6(EC50of 7.0 μM) receptors[1]. |
IC50& Target | EC50: 134 nM (P2Y2receptor), 9.3 μM (P2Y4receptor); 7.0 μM (P2Y6receptor)[1] |
体外研究 (In Vitro) | PSB-1114 (4-Thio-β,γ-difluoromethylene-UTP; compound 14g) displays >60-fold selectivity versus P2Y4 and P2Y6 receptors. Because of its high potency, selectivity, and expected metabolic stability toward ectonucleotidases, in particular NTPDases, PSB-1114 may be a useful pharmacological tool for studying P2Y2 receptors[1]. |
分子量 | 622.14 |
Formula | C10H11F2N2Na4O13P3S |
CAS 号 | 1657025-60-9 |
运输条件 | Room temperature in continental US; may vary elsewhere. |
储存方式 | Please store the product under the recommended conditions in the Certificate of Analysis. |