CAS NO: | 22204-24-6 |
包装 | 价格(元) |
10 mM * 1 mL in DMSO | 电议 |
100mg | 电议 |
500mg | 电议 |
1 g | 电议 |
5 g | 电议 |
生物活性 | Pyrantel pamoate (Pyrantel embonate) is an orally active anthelmintic and an agonist of thenicotinic acetylcholine receptor(nAChR). Pyrantel pamoate can cause spasmodic muscle paralysis in parasites. Pyrantel pamoate can be used in the study of parasitic infections such as ascariasis, hookworm infections, intestinal worms (pinworm infections), trichinosis and trichinosis[1][2]. | ||||||||||||||||
IC50& Target | Parasites[1][2]. | ||||||||||||||||
体外研究 (In Vitro) | Pyrantel pamoate (10 nM-10 μM; 72 h) shows good anti-A. suumand (0-168.2 M; 72 h) anti-N. americanusactivity[1][2]. Cell Viability Assay[1]
Cell Viability Assay[2]
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体内研究 (In Vivo) | Pyrantel pamoate (10 mg/kg; p.o.; single) reduces the worms inA. ceylanicum-infected hamsters, with the worm burden reduction of 87.2% and worm expulsion rate of 63.4%[2].
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Clinical Trial | |||||||||||||||||
分子量 | 594.68 | ||||||||||||||||
性状 | Solid | ||||||||||||||||
Formula | C34H30N2O6S | ||||||||||||||||
CAS 号 | 22204-24-6 | ||||||||||||||||
中文名称 | 双羟萘酸噻嘧啶;恩波酸噻嘧啶;抗虫灵;双羟萘酸喹嘧啶;双羟乃酸噻嘧啶 | ||||||||||||||||
运输条件 | Room temperature in continental US; may vary elsewhere. | ||||||||||||||||
储存方式 | 4°C, sealed storage, away from moisture *In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture) | ||||||||||||||||
溶解性数据 | In Vitro: DMSO : 20.83 mg/mL(35.03 mM;ultrasonic and warming and heat to 70℃) 配制储备液
* 请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液;一旦配成溶液,请分装保存,避免反复冻融造成的产品失效。 In Vivo: 请根据您的实验动物和给药方式选择适当的溶解方案。以下溶解方案都请先按照In Vitro方式配制澄清的储备液,再依次添加助溶剂: ——为保证实验结果的可靠性,澄清的储备液可以根据储存条件,适当保存;体内实验的工作液,建议您现用现配,当天使用;
以下溶剂前显示的百
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