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Vildagliptin-d3
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Vildagliptin-d3图片
CAS NO:1217546-82-1
包装与价格:
包装价格(元)
500 μg电议
5mg电议

产品名称
LAF237-d3
NVP-LAF 237-d3
产品介绍
Vildagliptin-d3 (LAF237-d3) 是 Vildagliptin 的氘代物。Vildagliptin (LAF237) 是一种有效且稳定的选择性二肽基肽酶IV (DPP-IV) 抑制剂,在人 Caco-2 细胞中抑制 DPP-IV 的IC50为 3.5 nM。Vildagliptin 具有出色的口服生物利用度和有效的降血糖活性。
生物活性

Vildagliptin-d3 (LAF237-d3) is the deuterium labeled Vildagliptin. Vildagliptin (LAF237) is a potent, stable, selectivedipeptidyl peptidaseIV (DPP-IV) inhibitor with anIC50of 3.5 nM in human Caco-2 cells. Vildagliptin possesses excellent oral bioavailability and potent antihyperglycemic activity[1][2].

体外研究
(In Vitro)

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].

分子量

306.42

Formula

C17H22D3N3O2

CAS 号

1217546-82-1

中文名称

维达列汀 d3

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.