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Glyco-Obeticholic Acid
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Glyco-Obeticholic Acid图片
CAS NO:863239-60-5
包装:5mg
市场价:5500元

产品介绍
Glyco-obeticholic acid 是牛磺酸的活性代谢物。Obeticholic Acid 是一种口服生物可利用的法尼样X受体 (FXR) 激动剂。
生物活性

Glyco-obeticholic acid is an active metabolite of Obeticholic acid. Obeticholic acid is a farnesoid X receptor (FXR) agonist[1].

体外研究
(In Vitro)

Obeticholic acid is conjugated with glycine in the liver to form glycol-obeticholic acid, which is secreted into bile. Microorganisms in the ileum and colon can deconjugate glyco-obeticholic acid, converting it into the parent drug, which may then be reabsorbed or excreted in faeces[1].

分子量

477.68

性状

Solid

Formula

C28H47NO5

CAS 号

863239-60-5

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式
Powder-20°C3 years
4°C2 years
In solvent-80°C6 months
-20°C1 month