Ambroxol-d5 (NA-872-d5) hydrochloride is the deuterium labeled Ambroxol hydrochloride. Ambroxol hydrochloride (NA-872 hydrochloride), an active metabolite of the prodrug Bromhexine, has potent expectorant effects. Ambroxol hydrochloride is aglucocerebrosidase (GCase)chaperone and increases glucocerebrosidase activity. Ambroxol hydrochloride induces lungautophagyand has the potential for Parkinson disease and neuronopathic Gaucher disease research^[1][2].

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs^[1].

419.59

C₁₃H₁₄D₅Br₂ClN₂O

2741380-71-0

盐酸氨溴索 d5 (盐酸盐)

Room temperature in continental US; may vary elsewhere.

Please store the product under the recommended conditions in the Certificate of Analysis.