包装 | 价格(元) |
100mg | 电议 |
250mg | 电议 |
500mg | 电议 |
生物活性 | LXRantagonist 2 (compound 10rr) is a potentLXR(liver X receptor) inverse agonist, withIC50values of 0.36 and 2.25 μM for LXRβ and LXRα, respectively.LXRantagonist 2 is a lipogenesis inhibitor through down-regulatingLXRtarget genes SREBP-1c, ACC,FASand SCD-1.LXRantagonist 2 shows lipid-lowering effects in mice with Triton WR-1339-induced hyperlipidemia[1]. |
IC50& Target | IC50: 0.36 ± 0.05 μM (LXRβ) 2.25 ± 0.58 μM (LXRα)[1] |
分子量 | 588.76 |
Formula | C34H40N2O5S |
运输条件 | Room temperature in continental US; may vary elsewhere. |
储存方式 | Please store the product under the recommended conditions in the Certificate of Analysis. |