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Spironolactone-d7
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Spironolactone-d7图片
包装与价格:
包装价格(元)
1mg电议
5mg电议

产品名称
SC9420-d7
产品介绍
Spironolactone-d7 (SC9420-d7) 是 Spironolactone 的氘代物。Spironolactone (SC9420) 是一种具有口服活性醛固酮盐皮质激素受体 (aldosterone mineralocorticoid receptor) 拮抗剂,IC50值为 24 nM。Spironolactone 也是雄激素受体 (androgen receptor) 拮抗剂,IC50
生物活性

Spironolactone-d7 (SC9420-d7) is the deuterium labeled Spironolactone. Spironolactone (SC9420) is an orally activealdosteronemineralocorticoid receptorantagonist with anIC50of 24 nM. Spironolactone is also a potent antagonist ofandrogen receptorwith anIC50of 77 nM. Spironolactone promotesautophagyin podocytes[1][2][3].

体外研究
(In Vitro)

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].

分子量

423.62

Formula

C24H25D7O4S

中文名称

螺内酯 d7

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.