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Eplerenone-d3
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Eplerenone-d3图片
包装与价格:
包装价格(元)
1mg电议
5mg电议

产品名称
Epoxymexrenone-d3
产品介绍
Eplerenone-d3 (Epoxymexrenone-d3) 是 Eplerenone 的氘代物。Eplerenone (Epoxymexrenone) 是一种选择性,竞争性和具有口服活性的醛固酮 (aldosterone) 拮抗剂,IC50为 138 nM。Eplerenone 对孕酮,雄激素,雌激素和糖皮质激素受体的亲和力低。Eplerenone 可用于高血压和心肌梗死后的心力衰竭的研究。
生物活性

Eplerenone-d3 (Epoxymexrenone-d3) is the deuterium labeled Eplerenone. Eplerenone (Epoxymexrenone) is a selective, competitive and oreally activealdosteroneantagonist with anIC50of 138 nM. Eplerenone has low affinity for progesterone, androgen, estrogen and glucocorticoid receptors. Eplerenone can be used for hypertension and heart failure after myocardial infarction reserch[1][2].

体外研究
(In Vitro)

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].

分子量

417.51

Formula

C24H27D3O6

中文名称

依普利酮 d3

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.