| CAS NO: | 1007392-69-9 |
| 包装 | 价格(元) |
| 100mg | 电议 |
| 250mg | 电议 |
| 500mg | 电议 |
| 生物活性 | ACT 178882 is a newRenininhibitor with anIC50of 1.4 nM. |
| IC50& Target | IC50: 1.4 nM (Renin)[1] |
| 体外研究 (In Vitro) | The median time to Cmax(tmax) for ACT 178882 is prolonged from 3.5 to 5.0 h by diltiazem whereas its apparent terminal half-life (t 1/2 ) is unaffected by diltiazem, 22.9 and 24.2 h for treatments A and B, respectively. Using treatment A as reference, the geometric mean ratio (90% CI) is 1.62 (1.36 to 1.94) for Cmaxand 2.02 (1.75 to 2.34) for AUC∞, indicating a significant interaction between ACT 178882 and diltiazem[2]. |
| 分子量 | 647.03 |
| Formula | C33H38Cl3N3O4 |
| CAS 号 | 1007392-69-9 |
| 运输条件 | Room temperature in continental US; may vary elsewhere. |
| 储存方式 | Please store the product under the recommended conditions in the Certificate of Analysis. |
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