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Lomefloxacin HCl
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Lomefloxacin HCl图片
CAS NO:98079-52-8
包装与价格:
包装价格(元)
10mM (in 1mL DMSO)电议
50mg电议

产品介绍
Lomefloxacin (SC47111A) hydrochloride 是一种广谱喹诺酮类抗生素,具有抗菌活性。
Cas No.98079-52-8
别名盐酸洛美沙星; SC47111A hydrochloride
化学名1-ethyl-6,8-difluoro-7-(3-methylpiperazin-1-yl)-4-oxoquinoline-3-carboxylic acid;hydrochloride
Canonical SMILESCCN1C=C(C(=O)C2=CC(=C(C(=C21)F)N3CCNC(C3)C)F)C(=O)O.Cl
分子式C17H19F2N3O3.HCl
分子量387.81
溶解度≥ 6.3mg/mL in Water with gentle warming
储存条件4°C, protect from light
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

Lomefloxacin hydrochloride is a fluoroquinolone antibiotic.Target: AntibacterialLomefloxacin hydrochloride is a bactericidal fluoroquinolone agent with activity against a wide range of gram-negative and gram-positive organisms. The bactericidal action of lomefloxacin results from interference with the activity of the bacterial enzymes DNA gyrase and topoisomerase IV, which are needed for the transcription and replication of bacterial DNA. DNA gyrase appears to be the primary quinolone target for gram-negative bacteria. Topoisomerase IV appears to be the preferential target in gram-positive organisms. Interference with these two topoisomerases results in strand breakage of the bacterial chromosome, supercoiling, and resealing. As a result DNA replication and transcription is inhibited [1].

References:
[1]. http://www.drugbank.ca/drugs/DB00978