CAS NO: | 2807477-26-3 |
包装 | 价格(元) |
100mg | 电议 |
250mg | 电议 |
500mg | 电议 |
生物活性 | Monoamine OxidaseB inhibitor 2 is a potent, reversible, orally active and selectivemonoamine oxidaseB (MAO-B)inhibitor with anIC50of 1.33 nM.Monoamine OxidaseB inhibitor 2 has antioxidant and anti-neuroinflammatory activities.Monoamine OxidaseB inhibitor 2 can across the blood-brain barrier (BBB), and can be used for Parkinson’s disease study[1]. | ||
IC50& Target |
| ||
体外研究 (In Vitro) | In cellular experiments, Monoamine Oxidase B inhibitor 2 (compound 8f; 0.5-10.0 μM) could significantly decrease the production of NO and TNF-α in LPS-stimulated BV-2 cells[1]. | ||
体内研究 (In Vivo) | In in vivo acute and subacute MPTP-induced mice model of Parkinson’s disease, Monoamine Oxidase B inhibitor 2 (compound 8f; 6.3-39.5 mg/kg; oral administration) could significantly improve most behavioral disorders, restore the dopamine content and decrease the MDA content in the mice striatum[1]. | ||
分子量 | 314.35 | ||
Formula | C19H19FO3 | ||
CAS 号 | 2807477-26-3 | ||
运输条件 | Room temperature in continental US; may vary elsewhere. | ||
储存方式 | Please store the product under the recommended conditions in the Certificate of Analysis. |