RWJ 56110 是一种有效的、选择性的、类似于肽的 PAR-1 激活和内化抑制剂(结合 IC50\u003d0.44 uM),对 PAR-2、PAR-3 或 PAR-4 没有影响。
Cas No. | 252889-88-6 |
化学名 | (S,Z)-4-amino-N-benzyl-2-((Z)-((S)-2-(((Z)-((1-(2,6-dichlorobenzyl)-3-(pyrrolidin-1-ylmethyl)-1H-indol-6-yl)imino)(hydroxy)methyl)amino)-3-(3,4-difluorophenyl)-1-hydroxypropylidene)amino)butanimidic acid dihydrochloride |
Canonical SMILES | ClC(C=CC=C1Cl)=C1CN2C=C(C3=C2C=C(/N=C(O)/N[C@@](/C(O)=N/[C@@](/C(O)=N/CC4=CC=CC=C4)([H])CCN)([H])CC5=CC(F)=C(F)C=C5)C=C3)CN6CCCC6.Cl.Cl |
分子式 | C41H43Cl2F2N7O3.2HCl |
分子量 | 863.65 |
溶解度 | water to 25 mM; DMSO to 100mM |
储存条件 | Store at -20°C |
General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
Shipping Condition | Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request |