Sonepiprazole (PNU-101387G) 是一种选择性 D4 多巴胺拮抗剂,对 rD4-Dopamine、hD4.2-Dopamine、rD2-Dopamine 和 Histamine-H1 受体的 Kis 分别为 3.6、10.1、5147 和 7430 nM。
Cas No. | 170858-33-0 |
别名 | PNU-101387G; U-101387G |
化学名 | (R)-4-(4-(2-(isochroman-1-yl)ethyl)piperazin-1-yl)benzenesulfonamide |
Canonical SMILES | O=S(N)(C1=CC=C(C=C1)N2CCN(CC2)CC[C@H]3OCCC4=CC=CC=C34)=O |
分子式 | C21H27N3O3S |
分子量 | 401.52 |
溶解度 | DMF: 30 mg/ml,DMSO: 30 mg/ml,Ethanol: 200µ g/ml |
储存条件 | Store at -20℃ |
General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
Shipping Condition | Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request |