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Platyconic acid A
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Platyconic acid A图片
CAS NO:68051-23-0
包装与价格:
包装价格(元)
5mg电议
10mg电议
50mg电议

产品介绍
Platyconic Acid A 是桔梗皂苷的活性成分,可用于减轻气道炎症的研究。
生物活性

Platyconic Acid A is an active component of changkil saponins fromplatycodon grandiflorumand can be used for the research of reducing airway inflammation[1].

体外研究
(In Vitro)

Platyconic Acid A (0.5~2 μM; 30 minutes; A549 cells) inhibits PMA-induced NF-κB p65 phosphorylation, IκBα phosphorylation and degradation and Akt phosphorylation in a concentration-dependent manner[1].
Platyconic Acid A (0.5~2 μM; 24 hours; A549 cells) decreases PMA-increased MUC5AC mRNA expression in a concentration-dependent manner[1].

Western Blot Analysis[1]

Cell Line:A549 cells
Concentration:0.5~2 μM
Incubation Time:30 minutes
Result:Inhibited PMA-induced NF-κB p65 phosphorylation, IκBα phosphorylation and degradation and Akt phosphorylation in a concentration-dependent manner.

RT-PCR[1]

Cell Line:A549 cells
Concentration:0.5~2 μM
Incubation Time:24 hours
Result:Decreased PMA-increased MUC5AC mRNA expression in a concentration-dependent manner.
分子量

1239.31

性状

Solid

Formula

C57H90O29

CAS 号

68051-23-0

结构分类
  • Terpenoids
  • Triterpenes
来源
  • Plants
  • Campanulaceae
  • Platycodon grandiflorus(Jacq.) A. DC.
运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

4°C, protect from light

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

溶解性数据
In Vitro: 

H2O : 25 mg/mL(20.17 mM;Need ultrasonic)

配制储备液
浓度溶剂体积质量1 mg5 mg10 mg
1 mM0.8069 mL4.0345 mL8.0690 mL
5 mM0.1614 mL0.8069 mL1.6138 mL
10 mM0.0807 mL0.4035 mL0.8069 mL
*

请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液;一旦配成溶液,请分装保存,避免反复冻融造成的产品失效
储备液的保存方式和期限:-80℃, 6 months; -20℃, 1 month (protect from light)。-80℃ 储存时,请在 6 个月内使用,-20℃ 储存时,请在 1 个月内使用。