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Scoparone
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Scoparone图片
CAS NO:120-08-1
包装与价格:
包装价格(元)
1mg电议
5mg电议
10mg电议
20mg电议

产品介绍
Scoparone 从毛蒿中分离出来的,具有抗凝血,抗血管舒张作用,抗炎活性。
Cas No.120-08-1
别名6,7-二甲氧基香豆素
Canonical SMILESO=C1C=CC2=CC(OC)=C(OC)C=C2O1
分子式C11H10O4
分子量206.19
溶解度DMSO: 62.5 mg/mL (303.12 mM)
储存条件Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

Scoparone is isolated from Artemisia capillaris, has anticoagulant, vasorelaxant antioxidant, anti-inflammatory activities[1].

Scoparone (0-0.4 nM; 24-48 hours) produces the most inhibition on PSC proliferation at 0.4 nM[1].

Scoparone (oral administration; 30 mg/kg, 60 mg/kg; 4 weeks) greatly ameliorates the pancreatic weight loss induced by DBTC in pancreatitis rats[1]. Animal Model: Chronic Pancreatitis (CP) Rat Models[1]

[1]. Xu M, et al. Scoparone Protects Against Pancreatic Fibrosis via TGF-β/Smad Signaling in Rats. Cell Physiol Biochem. 2016;40(1-2):277-286. Epub 2016 Nov 18.