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Cefoselis Sulfate
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Cefoselis Sulfate图片
CAS NO:122841-12-7
包装:50mg
市场价:515元

产品介绍
硫酸头孢塞利斯(FK-037)是第四代头孢菌素,是一种β-内酰胺类抗生素。
Cas No.122841-12-7
别名硫酸头孢噻利; FK-037
化学名(6R,7R)-7-[[(2E)-2-(2-amino-1,3-thiazol-4-yl)-2-methoxyiminoacetyl]amino]-3-[[2-(2-hydroxyethyl)-3-iminopyrazol-1-yl]methyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid;sulfuric acid
Canonical SMILESCON=C(C1=CSC(=N1)N)C(=O)NC2C3N(C2=O)C(=C(CS3)CN4C=CC(=N)N4CCO)C(=O)O.OS(=O)(=O)O
分子式C19H24N8O10S3
分子量620.64
溶解度≥ 62.1mg/mL in DMSO with gentle warming
储存条件4°C, protect from light, stored under nitrogen
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

Cefoselis sulfate is a widely used beta-lactam antibiotic.Target: AntibacterialCefoselis sulfate, a new parenteral cephalosporin, was active against clinical isolates of both gram-positive and gram-negative aerobic bacteria. The activity of Cefoselis (sulfate) was similar to that of cefpirome and cefepime and generally superior to that of ceftazidime. Cefoselis sulfate showed potent antibacterial activity against Hemophilus influenzae and Moraxella catarrhalis.Cefoselis sulfate was highly active against MSSA and MSCNS. Cefoselis sulfate was poor in the activity against MRSA,MRCNS,PRSP and Enterococcus faecalis,and no activity for Enterococcus faecium.

References:
[1]. ZHU, D., et al., In vitro activities of cefoselis compared to β-lactams and other antibacterial agents aganst gram-positive and gram-negative clinical isolates. Chinese Journal of Infection and Chemotherapy, 2011. 4: p. 002.
[2]. King, A., L. Bethune, and I. Phillips, The Comparative In Vitro Activity of FK-037 (Cefoselis), a New Broad-Spectrum Cephalosporin. Clin Microbiol Infect, 1995. 1(1): p. 13-17.