您好，欢迎来到试剂信息网！ [登录] [免费注册]
试剂信息网
发布求购
位置：首页 > 产品库 > Glutaminase C-IN-1
立即咨询
咨询类型：
     
*姓名：
*电话：
*单位：
Email：
*留言内容：
请详细说明您的需求。
*验证码：
 
Glutaminase C-IN-1
本产品不向个人销售，仅用作科学研究，不用于任何人体实验及非科研性质的动物实验。
Glutaminase C-IN-1图片
CAS NO:311795-38-7
包装与价格：
包装价格(元)
5mg电议
10mg电议
50mg电议

产品介绍
Glutaminase C-IN-1 (Compound 968) 是 Glutaminase C 的变构抑制剂，可抑制癌细胞生长而不影响其正常细胞对应物。
Cas No.311795-38-7
别名5-[3-溴-4-(二甲胺基)苯基]-2,3,5,6-四氢-2,2-二甲基苯并[A]菲啶-4(1H)-酮,Compound 968
Canonical SMILESO=C1C(C(C2=CC=C(N(C)C)C(Br)=C2)NC3=C4C5=CC=CC=C5C=C3)=C4CC(C)(C)C1
分子式C27H27BrN2O
分子量475.42
溶解度DMSO : 25 mg/mL (52.59 mM)
储存条件Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

Glutaminase C-IN-1 (968) is an allosteric inhibitor of Glutaminase C that inhibits cancer cell growth without affecting their normal cellular counterparts.

References:
[1]. Stalnecker CA, et al. Mechanism by which a recently discovered allosteric inhibitor blocks glutamine metabolism in transformed cells. Proc Natl Acad Sci U S A. 2015 Jan 13;112(2):394-9.