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Leukotriene F4
本产品不向个人销售，仅用作科学研究，不用于任何人体实验及非科研性质的动物实验。
Leukotriene F4图片
CAS NO:83851-42-7
包装与价格：
包装价格(元)
25μg电议
50μg电议
100μg电议

产品介绍
白三烯 F4 (LTF4) 是一种脂质，属于半胱氨酰白三烯 (CysTL) 家族。
Cas No.83851-42-7
别名白三烯,LTF4
化学名5S-hydroxy-6R-(S-γ-glutamylcysteinyl)-7E,9E,11Z,14Z-eicosatetraenoic acid
Canonical SMILESCCCCC/C=C\C/C=C\C=C\C=C\[C@@H](SC[C@H](NC(CC[C@H](N)C(O)=O)=O)C(O)=O)[C@@H](O)CCCC(O)=O
分子式C28H44N2O8S
分子量568.7
溶解度>50 mg/ml (per Ramki Iyer) in DMSO, >50 mg/ml (per Ramki Iyer) in DMF, >50 mg/ml (per Ramki Iyer) in Ethanol
储存条件Store at -80°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

LTF4 is a cysteinyl-leukotriene produced in vitro, but not reported to date in vivo. It is formed by the incubation of LTE4 with γ-glutamyl transpeptidase and glutathione. LTF4 is a weak agonist in its ability to contract vascular smooth muscle. [1] The rank order of potency of the cysteinyl-leukotrienes to contract vascular smooth muscle is LTD4 > LTC4 > LTE4 >> LTF4. [1] [2]

Reference:
[1]. Bernstrom, K., and Hammarstrom, S. A novel leukotriene formed by transpeptidation of leukotriene E4. Biochemical and Biophysical Research Communications 109, 800-804 (1982).
[2]. Lord, A., Charleson, S., and Letts, L.G. Leukotriene F4 and the release of arachidonic acid metabolites from perfused guinea pig lungs in vitro. Prostaglandins 29, 651-660 (1985).