Benocyclidine (BTCP) is a phencyclidine (PCP) derivative with a benzothiophenyl group instead of a phenyl ring. BTCP highly potently inhibited dopamine (DA) uptake with the IC50 of 7-8 nM. BTCP showed low affinity for the PCP receptor with the IC50 of 6 μM. In the striatum, BTCP binding was dose-dependently inhibited by unlabeled BTCP and nomifensine with the ID50 of 6.34 mg/kg and 11.06 mg/kg, respectively. BTCP bound to the dopamine uptake complex in the mouse brain in vivo

纯度：≥98%

CAS：112726-66-6