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VE-822
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
VE-822图片
CAS NO:1232416-25-9
包装与价格:
包装价格(元)
5mg电议
10mg电议
25mg电议
50mg电议
10mM * 1mL in DMSO电议

产品名称
VE822, VE 822
产品介绍

生物活性

VE-822是有效的ATR抑制剂。

靶点信息

ATR (HT29 cells)ATM (HT29 cells)
19 nM34 μM

化学数据

目录号A13289
作用机制Inhibitor (抑制剂)
M. Wt463.55
FormulaC24H25N5O3S
Purity>99%
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for36 months.
In solution, store at -20ºC and use within3 monthsto prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

CAS No.1232416-25-9
SynonymsVE822, VE 822
SMILESCC(C)S(=O)(=O)C1=CC=C(C=C1)C2=CN=C(C(=N2)C3=CC(=NO3)C4=CC=C(C=C4)CNC)N

溶解度

In vitro (25°C)DMSO36 mg/mL (77.66 mM)
WaterInsoluble
EthanolInsoluble
In vivo5% DMSO+45% PEG 300+H2O10 mg/mL
*<1 mg/ml means slightly soluble or insoluble.
*Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

储备液配制

Concentration / Solvent Volume / Mass1 mg5 mg10 mg
0.1 mM21.57 mL107.86 mL215.73 mL
0.5 mM4.31 mL21.57 mL43.15 mL
1 mM2.16 mL10.79 mL21.57 mL
5 mM0.43 mL2.16 mL4.31 mL

*The above data is based on the productmolecular weight 463.55. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.