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(+,-)-Octopamine HCl
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
(+,-)-Octopamine HCl图片
CAS NO:770-05-8
包装与价格:
包装价格(元)
10mM (in 1mL DMSO)电议
50mg电议

产品介绍
Octopamine ((῱)-p-Octopamine) hydrochloride 是一种在结构上与去甲肾上腺素相关的生物单胺,在无脊椎动物中充当神经激素、神经调节剂和神经递质。
Cas No.770-05-8
别名章胺盐酸盐; (±)-p-Octopamine hydrochloride
化学名4-(2-amino-1-hydroxyethyl)phenol;hydrochloride
Canonical SMILESC1=CC(=CC=C1C(CN)O)O.Cl
分子式C8H11NO2.HCl
分子量189.64
溶解度DMF: 12 mg/ml,DMSO: 12 mg/ml,Ethanol: 10 mg/ml,PBS (pH 7.2): 10 mg/ml
储存条件Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

Octopamine hydrochloride ((±)-p-Octopamine hydrochlorid) is an endogenous biogenic amine that is closely related to norepinephrine, and has effects on the adrenergic and dopaminergic systems.Target: Dopamine Receptor; Adrenergic ReceptorOctopamine is present in relatively high concentrations in neuronal as well as in non-neuronal tissues of most invertebrate species studied, and modulates almost every physiological process. Octopamine acts as neurohormone including desensitization of sensory inputs, influence on learning and memory, or regulation of the mood of the animal in the central nervous system. Octopamine is the only neuroactive non-peptide transmitter whose physiological role is restricted to invertebrates, and all octopamine receptors belong to the family of G-protein coupled receptors [1].Octopamine (10 μM) injected into the mushroom body (MB) calyces or the antennal lobe but not the lateral protocerebral lobe produces a lasting, pairing-specific enhancement of extension of the proboscis. Octopamine (10 μM) injected into the MB calyces results in an additional pairing-specific effect, because it does not lead to an acquisition but a consolidation after conditioning [2]. Octopamine treatment significantly elevates levels of octopamine in the brain and caused a significant dose-dependent increase in the number of new foragers. Octopamine treatment is effective only when given to bees old enough to forage, i.e., older than 4 days of age. Octopamine influences division of labor in honey bee colonies [3].

References:
[1]. Roeder, T., Octopamine in invertebrates. Prog Neurobiol, 1999. 59(5): p. 533-61.
[2]. Hammer, M. and R. Menzel, Multiple sites of associative odor learning as revealed by local brain microinjections of octopamine in honeybees. Learn Mem, 1998. 5(1-2): p. 146-56.
[3]. Schulz, D.J. and G.E. Robinson, Octopamine influences division of labor in honey bee colonies. J Comp Physiol A, 2001. 187(1): p. 53-61.