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Alprostadil
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Alprostadil图片
CAS NO:745-65-3
包装与价格:
包装价格(元)
10mM (in 1mL DMSO)电议
10mg电议
50mg电议

产品介绍
Alprostadil (Alprostadil) 是一种前列腺素受体配体,对小鼠 EP3、EP4、EP2、IP 和 EP1 的 Kis 分别为 1.1 nM、2.1 nM、10 nM、33 nM 和 36 nM。
Cas No.745-65-3
别名前列地尔; Alprostadil; PGE1
化学名7-[(1R,2R,3R)-3-hydroxy-2-[(E,3S)-3-hydroxyoct-1-enyl]-5-oxocyclopentyl]heptanoic acid
Canonical SMILESCCCCCC(C=CC1C(CC(=O)C1CCCCCCC(=O)O)O)O
分子式C20H34O5
分子量354.48
溶解度≥ 13.4mg/mL in DMSO
储存条件Store at -20°C, stored under nitrogen,unstable in solution, ready to use.
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

Prostaglandin E1 (PGE1) is a potent vasodilator and activates the prostaglandin E1 (EP) receptor.

References:
[1]. Cawello W, et al. Dose proportional pharmacokinetics of alprostadil (prostaglandin E1) in healthy volunteers following intravenous infusion. Br J Clin Pharmacol. 1995 Sep;40(3):273-6.
[2]. Roehl SL, et al. Alprostadil (Prostin VR Pediatric Sterile Solution, The Upjohn Company). Drug Intell Clin Pharm. 1982 Nov;16(11):823-32.
[3]. Harding LM, et al. Comparison of a needle-free high-pressure injection system with needle-tipped injection of intracavernosal alprostadil for erectile dysfunction. Int J Impot Res. 2002 Dec;14(6):498-501.