您好,欢迎来到试剂信息网! [登录] [免费注册]
试剂信息网
位置:首页 > 产品库 > Cefpiramide
立即咨询
咨询类型:
     
*姓名:
*电话:
*单位:
Email:
*留言内容:
请详细说明您的需求。
*验证码:
 
Cefpiramide
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Cefpiramide图片
CAS NO:70797-11-4
包装与价格:
包装价格(元)
100mg电议
250mg电议
500mg电议

产品名称
SM-1652 free acid
Wy-44635 free acid
产品介绍
Cefpiramide (SM-1652) free acid 是一种半合成头孢菌素,具有广谱抗菌活性。Cefpiramide free acid 对革兰氏阳性细菌和革兰氏阴性细菌均具有很强的抗菌活性。Cefpiramide free acid 对 β-内酰胺酶具有中度敏感性。
生物活性

Cefpiramide (SM-1652) free acid is a semisynthetic cephalosporin with broad-spectrum antibacterial activity. Cefpiramide free acid shows strong antibacterial effect on both gram-positive bacteria and gram-negative bacteria. Cefpiramide free acid is moderately susceptible to β-lactamase[1][2].

IC50& Target

Bacterial[1][2]

体外研究
(In Vitro)

Cefpiramide (0-2048 μg/mL; 16-18 hours) shows good activity to against most non-fermentative Gram-negative bacilli andEnterococci(32 μg/mL with 97% inhibition)[1].
Cefpiramide (0-2048 μg/mL; 16-18 hours) exhibits high effective to againstPseudomonas aeruginosawith MIC[50]and MIC[90]values of 4 μg/mL and 16 μg/mL separately[1].

Cell Viability Assay[1]

Cell Line:761 bacterial isolates (35 different species of common bacterial pathogens)
Concentration:0-2048 μg/mL
Incubation Time:16-18 hours
Result:Showed broad-spectrum antibacterial activity.
体内研究
(In Vivo)

Cefpiramide (25 mg/kg; i.v.; once) shows anti-Streptococcus pneumoniaeactivity in experimental pneumococcal meningitis[2].
Cefpiramide (25 mg/kg; i.v.; once) reduces bacteria in CSF more than 10[4]CFU/ml[2].

Animal Model:New Zealand white male rabbits(2-3 kg)[2].
Dosage:25 mg/kg
Administration:Intravenous injection; once.
Result:Anti-Streptococcus pneumoniae.
分子量

612.64

Formula

C25H24N8O7S2

CAS 号

70797-11-4

中文名称

头孢匹胺游离酸

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.